Potential contribution of the hepcidin-macrophage axis to plaque vulnerability in acute myocardial infarction in human

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• 作者：Masahiro Sasai^a ; ^b ; ¹ ; Yoshitaka Iso^a ; ^c ; ¹ ; ^{yiso@med.showa-u.ac.jp} ; Takuya Mizukami^a ; Naohisa Tomosugi^d ; Takeyuki Sambe^c ; Akira Miyazaki^b ; Hiroshi Suzuki^a
• 关键词：Hepcidin-25 ; Interleukin-6 ; Myocardial infarction ; Macrophages ; Plaque vulnerability
• 刊名：International Journal of Cardiology
• 出版年：2017
• 出版时间：15 January 2017
• 年：2017
• 卷：227
• 期：Complete
• 页码：114-121
• 全文大小：852 K
• 卷排序：227

文摘

Circulating Hepcidin-25 was elevated in acute myocardial infarction. Hepcidin-25 was produced from coronary plaque macrophages. Hepcidin-25 induced cell death of the cultured coronary-artery endothelial cells.