Increased expression of microRNA-21 in peripheral blood mediates the down-regulation of IFN-γ and increases the prevalence of stroke-associated infection
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- 作者：Shao-Peng Lina ; Shan Yeb ; Xiao-Hui Chena ; Hui-Lin Jianga ; Hai-Feng Maoa ; Mei-Ting Chena ; Qiu-Jie Maa ; Youming Longc ; Yongxiang Fanc ; Pei-Yi Lina ; linpeiyi@163.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Stroke ; MicroRNA-21 ; IFN-γ ; Infection
- 刊名：Journal of the Neurological Sciences
- 出版年：2016
- 出版时间：15 July 2016
- 年：2016
- 卷：366
- 期：Complete
- 页码：235-239
- 全文大小：413 K
文摘
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The SAI group had significantly higher plasma miRNA-21 and lower IFN-γ levels.
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There was a significant negative correlation between plasma miRNA-21 and IFN-γ.
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The optimal cutoff value was miRNA-21 > 0.53 and IFN-γ ≤ 72.57 pg/ml for predicting SAI.