Deleted in malignant brain tumors 1 protein is a potential biomarker of acute respiratory distress syndrome induced by pneumonia
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- 作者：Shan Rena ; b ; rs1226@sina.com" class="auth_mail" title="E-mail the corresponding author ; Xia Chena ; chenxiayuanmeng@163.com" class="auth_mail" title="E-mail the corresponding author ; Li Jianga ; jiangli@sina.com" class="auth_mail" title="E-mail the corresponding author ; Bo Zhua ; zhubo123123@sina.com" class="auth_mail" title="E-mail the corresponding author ; Qi Jianga ; jiangqi7676@sina.com" class="auth_mail" title="E-mail the corresponding author ; Xiuming Xia ; xxm2937@sina.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：ARDS ; iTRAQ ; Mass spectrometry ; Biomarkers ; Proteomics
- 刊名：Biochemical and Biophysical Research Communications
- 出版年：2016
- 出版时间：23 September 2016
- 年：2016
- 卷：478
- 期：3
- 页码：1344-1349
- 全文大小：469 K
文摘
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We identified candidate biomarkers for early ARDS diagnosis and risk assessment.
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Eighteen proteins significantly differed in BALFs of mild and severe ARDS patients.
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Differential plasma expression of apoA1, SP-A, and DMBT1 was confirmed in ARDS.
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DMBT1 may be useful for early ARDS diagnosis and predicting disease severity.