Postoperative Complications in the Ahmed Baerveldt Comparison Study During Five Years of Follow-up

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• 作者：Donald L. Budenz^a ; ^{dbudenz@med.unc.edu" class="auth_mail" title="E-mail the corresponding author}Author Vitae ; William J. Feuer^b ; Keith Barton^c ; ^d ; Joyce Schiffman^b ; Vital P. Costa^e ; David G. Godfrey^f ; Yvonne M. Buys^g ; on behalf of the Ahmed Baerveldt Comparison Study GroupDonald Budenz ; MD ; MPH ; Steven J. Gedde ; MD ; Fouad El Sayyad ; MD ; Leon Herndon ; MD ; David Godfrey ; MD ; Ronald Fellman ; MD ; James Robinson ; MD ; David Dueker ; MD ; Patrick Riedel ; MD ; Thomas Samuelson ; MD ; Keith Barton ; MD ; Renata Puertas ; MD ; Paul Chew ; MD ; Cecilia Aquino ; MD ; Alfred M. Solish ; MD ; Yvonne Buys ; MD ; Graham Trope ; MD ; James D. Brandt ; MD ; Michele Lim ; MD ; Simon Law ; MD ; Vital Costa ; MD ; Steve Sarkisian ; MD ; Vikas Chopra ; MD ; Brian Francis ; MD ; Mario Meallet ; MD ; Rohit Varma ; MD ; MPH ; Peter Netland ; MD ; PhD ; Sarwat Salim ; MD ; Robert Feldman ; MD ; Nicholas Bell ; MD ; Philip Chen ; MD ; Dale Heuer ; MD ; Kuldev Singh ; MD ; MPH ; Martha Wright ; MD ; Donald L. Budenz ; MD ; MPH ; William J. Feuer ; MS ; Joyce C. Schiffman ; MS ; Keith Barton ; MD ; Donald L. Budenz ; MD ; MPH ; William J. Feuer ; MS ; William J. Feuer ; MS ; Joyce C. Schiffman ; MS ; Wei Shi ; MS ; Luz Ajuria ; Yolanda Silva ; BS
• 刊名：American Journal of Ophthalmology
• 出版年：2016
• 出版时间：March 2016
• 年：2016
• 卷：163
• 期：Complete
• 页码：75-82.e3
• 全文大小：704 K

文摘

To compare the late complications in the Ahmed Baerveldt Comparison Study during 5 years of follow-up.

Design

Multicenter, prospective randomized clinical trial.

Methods

setting: Sixteen international clinical centers. study population: Two hundred seventy-six subjects aged 18-85 years with previous intraocular surgery or refractory glaucoma with intraocular pressure of >18 mm Hg. interventions: Ahmed Glaucoma Valve FP7 or Baerveldt Glaucoma Implant BG 101-350. main outcome measures: Late postoperative complications (beyond 3 months), reoperations for complications, and decreased vision from complications.

Results

Late complications developed in 56 subjects (46.8 ± 4.8 5-year cumulative % ± SE) in the Ahmed Glaucoma Valve group and 67 (56.3 ± 4.7 5-year cumulative % ± SE) in the Baerveldt Glaucoma Implant group (P = .082). The cumulative rates of serious complications were 15.9% and 24.7% in the Ahmed Glaucoma Valve and Baerveldt Glaucoma Implant groups, respectively (P = .034), although this was largely driven by subjects who had tube occlusions in the 2 groups (0.8% in the Ahmed Glaucoma Valve group and 5.7% in the Baerveldt Glaucoma Implant group, P = .037). Both groups had a relatively high incidence of persistent diplopia (12%) and corneal edema (20%), although half of the corneal edema cases were likely due to pre-existing causes other than the aqueous shunt. The incidence of tube erosion was 1% and 3% in the Ahmed Glaucoma Valve and Baerveldt Glaucoma Implant groups, respectively (P = .04).

Conclusions

Long-term rates of vision-threatening complications and complications resulting in reoperation were higher in the Baerveldt Glaucoma Implant than in the Ahmed Glaucoma Valve group over 5 years of follow-up.