Associations of urinary metal levels with serum hormones, spermatozoa apoptosis and sperm DNA damage in a Chinese population
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- 作者：Yi-Xin Wanga ; b ; 1 ; Yang Suna ; b ; 1 ; Zhen Huanga ; b ; Peng Wangc ; Wei Fenga ; b ; Jin Lia ; b ; Pan Yanga ; b ; Mu Wangb ; Li Suna ; b ; Ying-Jun Chena ; b ; Chong Liua ; b ; Jing Yued ; Long-Jie Gud ; Qiang Zenga ; b ; zengqiang506@163.com" class="auth_mail" title="E-mail the corresponding author ; Wen-Qing Lua ; b ; luwq@mails.tjmu.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Metals ; Spermatozoa ; Apoptosis ; DNA damage ; Reproductive hormone ; Epidemiology
- 刊名：Environment International
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：94
- 期：Complete
- 页码：177-188
- 全文大小：1489 K
文摘
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We measured 18 heavy metals in repeated urine samples as exposure markers.
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Associations of the metals with hormones and sperm DNA integrity were assessed.
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Tin, nickel, zinc and molybdenum were inversely associated with T or T/LH ratio.
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Manganese was positively associated with percentage of Annexin V +/PI- spermatozoa.
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Urinary iron was inversely associated with percentage of PI + spermatozoa.
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