Effects of soluble and particulate Cr(VI) on genome-wide DNA methylation in human B lymphoblastoid cells
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- 作者：Jianlin Lou ; jianlinlou@163.com" class="auth_mail" title="E-mail the corresponding author ; Yu Wang ; Junqiang Chen ; Li Ju ; Min Yu ; Zhaoqiang Jiang ; Lingfang Feng ; Lingzhi Jin ; Xing Zhang ; xingtyou@mail.hz.zj.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Hexavalent chromium ; Cytotoxicity ; DNA methylation ; Human B lymphoblastoid cells
- 刊名：Mutation Research/Genetic Toxicology and Environmental Mutagenesis
- 出版年：2015
- 出版时间：October 2015
- 年：2015
- 卷：792
- 期：Complete
- 页码：12-18
- 全文大小：1055 K
文摘
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Cr(VI) induced a small amount of differentially methylated sites in human B lymphoblastoid cells.
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DNA methylation changes correlated with mRNA expression for four genes.
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DNA methylation changes did not correlate with mRNA expression for six genes.