Rh-catalyzed asymmetric hydrogenation of racemic aldimines via dynamic kinetic resolution

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• 作者：Dongyang Fan^a ; ^&dagger ; ; Jian Lu^b ; ^&dagger ; ; Yang Liu^a ; Zhenfeng Zhang^a ; ^{zhenfeng@sjtu.edu.cn" class="auth_mail" title="E-mail the corresponding author} ; Yangang Liu^a ; Wanbin Zhang^a ; ^b ; ^{wanbin@sjtu.edu.cn" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Asymmetric hydrogenation ; Dynamic kinetic resolution ; Chiral arylglycines ; Racemic aldimines ; Rhodium complex
• 刊名：Tetrahedron
• 出版年：2016
• 出版时间：1 September 2016
• 年：2016
• 卷：72
• 期：35
• 页码：5541-5547
• 全文大小：525 K

文摘

Catalyzed by a rhodium complex of P-stereogenic diphosphine ligand trichickenfootphos (TCFP), asymmetric hydrogenation of racemic aldimines via dynamic kinetic resolution has been realized for the preparation of chiral arylglycines with good yields and enantioselectivities.