Investigating composite systems based on poly l-lactide and poly l-lactide/triclosan nanoparticles for tissue engineering and medical applications
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- 作者：Seyed Mohammad Davachia ; Babak Kaffashia ; kaffashi@ut.ac.ir" class="auth_mail" title="E-mail the corresponding author ; Ali Zamanianb ; Bahman Torabinejadb ; Zhila Ziaeiradc
- 关键词：PLLA ; Triclosan ; Hydrolytic degradation kinetics ; Mechanical/thermal properties ; Cell culture
- 刊名：Materials Science & Engineering C
- 出版年：2016
- 出版时间：1 January 2016
- 年：2016
- 卷：58
- 期：Complete
- 页码：294-309
- 全文大小：2922 K
文摘
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Antibacterial composites with encapsulated drug were fabricated via melt blending.
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Accelerated hydrolytic degradation kinetics was obtained using a novel method.
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Incorporation of LATC30 increases hydrolytic degradation rate and hydrophilicity.
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Activation energy and crystallinity both decreased upon addition of LATC30.
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Optimum composite is suitable for bone tissue engineering and medical applications.