Circulating midkine in children with Henoch-Schönlein purpura: Clinical implications
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- 作者：Zhantao Sua ; b ; Xin Lva ; Yi Liua ; Jinhang Zhanga ; Jingyun Guana ; Zhongtao Gaia ; gaizhongtao@sina.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Midkine ; Henoch&ndash ; Schö ; nlein purpura ; Henoch&ndash ; Schö ; nlein purpura nephritis ; Biomarker
- 刊名：International Immunopharmacology
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：39
- 期：Complete
- 页码：246-250
- 全文大小：338 K
文摘
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This is the first report on midkine (MK) in children with HSP.
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Serum midkine level was elevated at the onset of the disease in children with HSP.
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There is an abnormal production of cytokines in children with HSP.
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MK positively correlated with IL-4, IL-6, IL17A, IgA and IgE.
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MK could be used as an efficient indicator for an early diagnosis of HSPN.