MicroRNA-340 inhibits the proliferation and invasion of hepatocellular carcinoma cells by targeting JAK1

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• 作者：Jianyong Yuan^a ; ¹ ; Hongxiang Ji^b ; ¹ ; Feng Xiao^a ; Zhipeng Lin^a ; Xijun Zhao^a ; Zhouchong Wang^a ; Jun Zhao^b ; ^{1239635303@qq.com} ; Junhua Lu^a ; ^{lujh0810@126.com}
• 关键词：miR-340 ; Hepatocellular carcinoma ; JAK1/STAT3 pathway ; Proliferation ; Invasion
• 刊名：Biochemical and Biophysical Research Communications
• 出版年：2017
• 出版时间：29 January 2017
• 年：2017
• 卷：483
• 期：1
• 页码：578-584
• 全文大小：2101 K
• 卷排序：483

文摘

miR-340 is downregulated in HCC and suppresses HCC cell proliferation, migration, and invasion. miR-340 overexpression on HCC xenograft tumor growth in nude mice. miR-340 directly targets JAK1. miR-340 regulates the JAK1/STAT3 signaling pathway.