Erythropoeitin Signaling in Macrophages Promotes Dying Cell Clearance and Immune Tolerance
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- 作者：Bangwei Luo1 ; Woting Gan1 ; Zongwei Liu1 ; Zigang Shen1 ; Jinsong Wang1 ; Rongchen Shi1 ; Yuqi Liu1 ; Yu Liu1 ; Man Jiang1 ; Zhiren Zhang1 ; zhangzhiren@yahoo.com" class="auth_mail" title="E-mail the corresponding author ; Yuzhang Wu1 ; wuyuzhang@yahoo.com" class="auth_mail" title="E-mail the corresponding author
- 刊名：Immunity
- 出版年：2016
- 出版时间：16 February 2016
- 年：2016
- 卷：44
- 期：2
- 页码：287-302
- 全文大小：4166 K
文摘
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Dying cell-released S1P activates macrophage EPO signaling in vitro and in vivo
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Macrophage EPO signaling is central for the immunosilent disposal of dying cells
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EPO enhances dying cell clearance through upregulating PPARγ in macrophages
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Macrophage-specific Epor−/− mice develope age-dependent lupus-like symptoms