Identification and functional characterization of a glucose regulated protein 94 gene in Litopenaeus vannamei and its responsiveness in WSSV infection
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- 作者：Hai-Tao Bib ; c ; Feng-Hua Yuanb ; c ; Kai Yuanb ; c ; Shao-Ping Wengb ; c ; Jian-Guo Hea ; b ; c ; Yi-Hong Chena ; c ; chenyh6@mail.sysu.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Litopenaeus vannamei ; ER-stress ; Unfolded protein response ; White spot syndrome virus ; Glucose regulated protein 94
- 刊名：Molecular Immunology
- 出版年：2016
- 出版时间：May 2016
- 年：2016
- 卷：73
- 期：Complete
- 页码：29-36
- 全文大小：2502 K
文摘
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Identification and characterization of a glucose regulated protein 94 in Litopenaeus vannamei (designated as LvGRP94).
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Promoter of LvGRP94 was activated by L. vannamei X-box binding protein 1 or heat shock treatment in S2 cells.
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Expression of LvGRP94 was induced by WSSV infection or unfolded protein response pathway activation.
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Knocked-down LvGRP94 reduced the mortality of L. vannamei upon WSSV infection.