Atrioventricular septal defect: From embryonic development to long-term follow-up
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- 作者：Emmeline E. Calkoena ; 1 ; Mark G. Hazekampb ; 1 ; Nico A. Blomc ; 1 ; Bernadette B.L.J. Eldersc ; 1 ; Adriana C. Gittenberger-de Grootd ; 1 ; Monique C. Haake ; 1 ; Margot M. Bartelingsf ; 1 ; Arno A.W. Roestc ; 1 ; 2 ; Monique R.M. Jongbloedd ; 1 ; 2 ; m.r.m.jongbloed@lumc.nl" class="auth_mail" title="E-mail the corresponding author
- 关键词：Atrioventricular septal defect ; Endocardial cushion defect ; Congenital heart disease
- 刊名：International Journal of Cardiology
- 出版年：2016
- 出版时间：1 January 2016
- 年：2016
- 卷：202
- 期：Complete
- 页码：784-795
- 全文大小：2549 K
文摘
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AVSD comprises a heterogeneous group of congenital defects.
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Abnormal endocardial cushion, mesenchymal cap and DMP development may result in AVSD.
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Genetic and maternal risk factors for AVSD and developmental aspects are discussed.
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AV-valve regurgitation after correction is common and can be assessed with 4DFlow MRI.
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Non-syndromic and Down syndrome patients have different anatomy and outcome.