Evaluation of antimicrobial photodynamic therapy with indocyanine green and curcumin on human gingival fibroblast cells: An in vitro photocytotoxicity investigation
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- 作者：M. Pourhajibaghera ; 1 ; N. Chiniforushb ; 1 ; S. Parkerc ; S. Shahabid ; R. Ghorbanzadehe ; M.J. Kharazifardf ; A Bahadora ; b ; f ; abahador@tums.ac.ir" class="auth_mail" title="E-mail the corresponding author ; ab.bahador@gmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Human gingival fibroblasts ; Photodynamic therapy ; Cytotoxic effect ; Cell viability ; Indocyanine green ; Curcumin
- 刊名：Photodiagnosis and Photodynamic Therapy
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：15
- 期：Complete
- 页码：13-18
- 全文大小：1168 K
文摘
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To avoid cytotoxicity, considering the concentration of PSs and laser irradiation time is essential for aPDT as an alternative treatment in the management of periodontal disease.
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When aPDT was used, the cell viability decreased with increasing exposure time of laser and decreasing concentrations of ICG.
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The cell cytotoxicity during aPDT with the lowest concentrations of curcumin is much higher than that in other groups.