DCIR negatively regulates CpG-ODN-induced IL-1β and IL-6 production
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- 作者：Xibao Zhaoa ; Yaping Shena ; Weiwei Hub ; Junru Chena ; Tian Wua ; Xiaoqiang Suna ; Juan Yua ; Tingting Wua ; Weilin Chena ; cwl@zju.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：C-type lectin receptors (CLR) ; Dendritic cell immunoreceptor (DCIR) ; Toll like receptors (TLR)
- 刊名：Molecular Immunology
- 出版年：2015
- 出版时间：December 2015
- 年：2015
- 卷：68
- 期：2
- 页码：641-647
- 全文大小：1611 K
文摘
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CpG-ODN up-regulates DCIR expression in macrophages.
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DCIR inhibits CpG-ODN-induced proinflammatory cytokine production.
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DCIR negatively regulates CpG-ODN-induced activation of MAPK signaling.