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Bimetallic Pt/Pd encapsulated mesoporous-hollow CeO2 nanospheres for signal amplification toward electrochemical peptide-based biosensing for matrix metalloproteinase 2
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A sensitive MMP-2 biosensor was constructed based on specific cleavage of peptide.

Pt/Pd/mhCeO2NS was used as nanocarriers and electrocatalysts for the biosensor.

The transduction of peptide cleavage events was combined with the electrocatalysts.

The catalytic capacity of Pt/Pd/mhCeO2NS was optimal to the signal amplification.

The electrochemical analytical performance was significantly improved and enhanced.

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