Altered expression of miR-125a-5p in thymoma-associated myasthenia gravis and its down-regulation of foxp3 expression in Jurkat cells
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- 作者：Jinpin Li1 ; lijinpin009@163.com" class="auth_mail" title="E-mail the corresponding author ; Di Qiu1 ; qiudi.happy@163.com" class="auth_mail" title="E-mail the corresponding author ; Zezhi Chen ; Weiwei Du ; Jingli Liu ; Xuean Mo
- 关键词：Myasthenia gravis (MG) ; Thymoma ; MiR-125a-5p ; Foxp3
- 刊名：Immunology Letters
- 出版年：2016
- 出版时间：April 2016
- 年：2016
- 卷：172
- 期：Complete
- 页码：47-55
- 全文大小：2262 K
文摘
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We identified 137 miRNAs differentially expressed in thymoma of TAMG patients.
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MiR-125a-5 was one of upregulated miRNAs in 137 dysregulated miRNAs.
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MiR-125a-5p can target foxp3 3′UTR.
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MiR-125a-5p may be involved in the thymic pathogenesis of TAMG by targeting foxp3.