Nanoparticles of Fluorescent Conjugated Polymers: Novel Ion-Selective Optodes

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• 作者：Katarzyna Kłucińska ; Emilia Stelmach ; Anna Kisiel ; Krzysztof Maksymiuk ; Agata Michalska
• 刊名：Analytical Chemistry
• 出版年：2016
• 出版时间：June 7, 2016
• 年：2016
• 卷：88
• 期：11
• 页码：5644-5648
• 全文大小：285K
• 年卷期：0
• ISSN：1520-6882

文摘

A novel type of ion-selective nano-optode is proposed, in which a conjugated polymer is used as optical transducer and nanoprobe material. Thus, contrary to most of the proposed optodes, the response does not require presence of pH-sensitive dye in the sensor. The conjugated polymer nanosensor material is in partially oxidized form—it is bearing positive charges and its emission is quenched. The receptor is an optically silent uncharged ionophore selective for the analyte cation. When a binding event occurs, positive charges are formed in the nanosphere, leading to a decrease in the oxidation state of the polymer, in the absence of redox potential change, resulting in increased emission. This general approach herein proposed results in a simple sensor, benefitting from a novel optical transduction mechanism and high lipophilicity of the polymer matrix that results in linear responses over a broad concentration range of analyte. For the model system studied, the linear dependence of emission intensity on the logarithm of analyte (K⁺) concentration was obtained for a broad range from 10^–5 M to 0.1 M.