Stereocontrolled First Total Syntheses of Amarouciaxanthin A and B

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• 作者：Yumiko Yamano ; Mahankhali Venu Chary ; Akimori Wada
• 刊名：Organic Letters
• 出版年：2013
• 出版时间：October 18, 2013
• 年：2013
• 卷：15
• 期：20
• 页码：5310-5313
• 全文大小：320K
• 年卷期：v.15,no.20(October 18, 2013)
• ISSN：1523-7052

文摘

The first total syntheses of amarouciaxanthin A and B (C₄₀) via the stereoselective Wittig reaction of C₁₅-allenic and C₁₅-acetylenic tri-n-butylphosphonium salts with the unprecedented C₂₅-3,8-dihydroxy-5,6-epoxyapocarotenal have been completed. Oxidation of the two hydroxyl groups in the left part of the resulting condensation products followed by regioselective oxirane ring opening gave the target carotenoids.