Defining the Catechol–Cation Synergy for Enhanced Wet Adhesion to Mineral Surfaces

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• 作者：Michael V. Rapp ; Greg P. Maier ; Howard A. Dobbs ; Nicholas J. Higdon ; J. Herbert Waite ; Alison Butler ; Jacob N. Israelachvili
• 刊名：Journal of the American Chemical Society
• 出版年：2016
• 出版时间：July 27, 2016
• 年：2016
• 卷：138
• 期：29
• 页码：9013-9016
• 全文大小：324K
• 年卷期：0
• ISSN：1520-5126

文摘

Mussel foot proteins (Mfps) exhibit remarkably adaptive adhesion and bridging between polar surfaces in aqueous solution despite the strong hydration barriers at the solid–liquid interface. Recently, catechols and amines—two functionalities that account for >50 mol % of the amino acid side chains in surface-priming Mfps—were shown to cooperatively displace the interfacial hydration and mediate robust adhesion between mineral surfaces. Here we demonstrate that (1) synergy between catecholic and guanidinium side chains similarly promotes adhesion, (2) increasing the ratio of cationic amines to catechols in a molecule reduces adhesion, and (3) the catechol–cation synergy is greatest when both functionalities are present within the same molecule.