Phytotoxins from the Leaves of Ruta graveolens
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- 作者：Amber L. Hale ; Kumudini M. Meepagala ; Anna Oliva ; Giovanni Aliotta ; and Stephen O. Duke
- 刊名：Journal of Agricultural and Food Chemistry
- 出版年：2004
- 出版时间：June 2, 2004
- 年：2004
- 卷：52
- 期：11
- 页码：3345 - 3349
- 全文大小：168K
- 年卷期：v.52,no.11(June 2, 2004)
- ISSN：1520-5118
文摘
Bioassay-guided fractionation of the ethyl acetate extract of Ruta graveolens (common rue) leavesled to the isolation of the furanocoumarins 5-methoxypsoralen (5-MOP), 8-methoxypsoralen (8-MOP),and the quinolone alkaloid graveoline as phytotoxic constituents. Graveoline and 8-MOP substantiallyinhibited growth of Lactuca sativa (lettuce) seedlings and reduced chlorophyll content at 100 
M;this effect was not due to a direct effect on chlorophyll synthesis. Radical growth of L. sativa wasinhibited by 10 M 8-MOP. Graveoline inhibited growth of Lemna paucicostata (duckweed) at 100M. This is the first report of the phytotoxic activity of graveoline. Growth of Agrostis stolonifera(bentgrass) was inhibited by 5-MOP at 30 M. All three compounds substantially reduced cell divisionin Allium cepa (onion) at or below 100 M. None of the compounds caused significant cellular leakageof Cucumis sativus (cucumber) cotyledon disks at 100 M. All three compounds inhibit plant growth,at least partially through inhibition of cell division.Keywords: Ruta graveolens; furanocoumarins; quinolone alkaloid; phytotoxin
M;this effect was not due to a direct effect on chlorophyll synthesis. Radical growth of L. sativa wasinhibited by 10 M 8-MOP. Graveoline inhibited growth of Lemna paucicostata (duckweed) at 100M. This is the first report of the phytotoxic activity of graveoline. Growth of Agrostis stolonifera(bentgrass) was inhibited by 5-MOP at 30 M. All three compounds substantially reduced cell divisionin Allium cepa (onion) at or below 100 M. None of the compounds caused significant cellular leakageof Cucumis sativus (cucumber) cotyledon disks at 100 M. All three compounds inhibit plant growth,at least partially through inhibition of cell division.Keywords: Ruta graveolens; furanocoumarins; quinolone alkaloid; phytotoxin