Diastereoselective Hydroformylation of 2,5-Cyclohexadienyl-1-carbinols with Catalytic Amounts of a Reversibly Bound Directing Group

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• 作者：Ippei Usui ; Kenichi Nomura ; Bernhard Breit
• 刊名：Organic Letters
• 出版年：2011
• 出版时间：February 18, 2011
• 年：2011
• 卷：13
• 期：4
• 页码：612-615
• 全文大小：705K
• 年卷期：v.13,no.4(February 18, 2011)
• ISSN：1523-7052

文摘

A phosphinite plays a role as a reversibly bound directing group for the regio- and diastereoselective hydroformylation of 2,5-cyclohexadienyl-1-carbinols. Of the two alkene functions only one was functionalized through hydroformylation to form a synthetically attractive quaternary carbon center leaving the second alkene function for potential further functionalization.