Nickel-Catalyzed Ring-Opening Alkylative Coupling of Enone with Methylenecyclopropane in the Presence of Triethylborane

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• 作者：Kenichi Ogata ; Daisuke Shimada ; Shouichi Furuya ; Shin-ichi Fukuzawa
• 刊名：Organic Letters
• 出版年：2013
• 出版时间：March 15, 2013
• 年：2013
• 卷：15
• 期：6
• 页码：1182-1185
• 全文大小：268K
• 年卷期：v.15,no.6(March 15, 2013)
• ISSN：1523-7052

文摘

Nickel-catalyzed alkylative coupling of an enone or enal with methylenecyclopropane in the presence of triethylborane was achieved via stereospecific proximal C鈥揅 bond cleavage of methylenecyclopropane. With the use of methylenecyclopropane possessing an acyclic alkyl substituent, this reaction was also accompanied by the 尾-hydrogen elimination.