Acaricidal Activity of Clove Bud Oil Compounds against Dermatophagoides farinae and Dermatophagoides pteronyssinus (Acari: Pyroglyphidae)
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- 作者：Eun-Hee Kim ; Hyun-Kyung Kim ; and Young-Joon Ahn
- 刊名：Journal of Agricultural and Food Chemistry
- 出版年：2003
- 出版时间：February 12, 2003
- 年：2003
- 卷：51
- 期：4
- 页码：885 - 889
- 全文大小：52K
- 年卷期：v.51,no.4(February 12, 2003)
- ISSN：1520-5118
文摘
The acaricidal activity of clove (Eugenia caryophyllata) bud oil-derived eugenol and its congeners(acetyleugenol, isoeugenol, and methyleugenol) against adults of Dermatophagoides farinae andDermatophagoides pteronyssinus was examined using direct contact application and fumigationmethods and compared with those of benzyl benzoate and N,N-diethyl-m-toluamide (DEET).Responses varied according to compound, dose, and mite species. On the basis of LD50 values, thecompound most toxic to D. farinae adults was methyleugenol (0.94 
g/cm2) followed by isoeugenol(5.17 g/cm2), eugenol (5.47 g/cm2), benzyl benzoate (9.22 g/cm2), and acetyleugenol (14.16 g/cm2). Very low activity was observed with DEET (37.59 g/cm2). Against D. pteronyssinus adults,methyleugenol (0.67 g/cm2) was much more effective than isoeugenol (1.55 g/cm2), eugenol (3.71g/cm2), acetyleugenol (5.41 g/cm2), and benzyl benzoate (6.59 g/cm2). DEET (17.85 g/cm2)was least toxic. These results indicate that the lipophilicity of the four phenylpropenes plays a crucialrole in dust mite toxicity. The typical poisoning symptom of eugenol and its congeners was a similardeath symptom of the forelegs extended forward together, leading to death without knockdown,whereas benzyl benzoate and DEET caused death following uncoordinated behavior. In a fumigationtest with both mite species, all four phenylpropenes were much more effective in closed containersthan in open ones, indicating that the mode of delivery of these compounds was largely due to actionin the vapor phase. Eugenol and its congeners merit further study as potential house dust mite controlagents or as lead compounds.Keywords: Natural acaricide; natural fumigant; Dermatophagoides farinae; Dermatophagoides pteronyssinus; Eugenia caryophyllata; clove bud oil, mode of action; poisoning symptom
g/cm2) followed by isoeugenol(5.17 g/cm2), eugenol (5.47 g/cm2), benzyl benzoate (9.22 g/cm2), and acetyleugenol (14.16 g/cm2). Very low activity was observed with DEET (37.59 g/cm2). Against D. pteronyssinus adults,methyleugenol (0.67 g/cm2) was much more effective than isoeugenol (1.55 g/cm2), eugenol (3.71g/cm2), acetyleugenol (5.41 g/cm2), and benzyl benzoate (6.59 g/cm2). DEET (17.85 g/cm2)was least toxic. These results indicate that the lipophilicity of the four phenylpropenes plays a crucialrole in dust mite toxicity. The typical poisoning symptom of eugenol and its congeners was a similardeath symptom of the forelegs extended forward together, leading to death without knockdown,whereas benzyl benzoate and DEET caused death following uncoordinated behavior. In a fumigationtest with both mite species, all four phenylpropenes were much more effective in closed containersthan in open ones, indicating that the mode of delivery of these compounds was largely due to actionin the vapor phase. Eugenol and its congeners merit further study as potential house dust mite controlagents or as lead compounds.Keywords: Natural acaricide; natural fumigant; Dermatophagoides farinae; Dermatophagoides pteronyssinus; Eugenia caryophyllata; clove bud oil, mode of action; poisoning symptom