An Efficient and Straightforward Access to Sulfur Substituted [2.2]Paracyclophanes: Application to Stereoselective Sulfenate Salt Alkylation

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• 作者：Jean-Franç ; ois Lohier ; Florian Foucoin ; Paul-Alain Jaffrè ; s ; Jos&eacute ; I. Garcia ; Jana Sopková ; -de Oliveira Santos ; St&eacute ; phane Perrio ; Patrick Metzner
• 刊名：Organic Letters
• 出版年：2008
• 出版时间：March 20, 2008
• 年：2008
• 卷：10
• 期：6
• 页码：1271 - 1274
• 全文大小：97K
• 年卷期：v.10,no.6(March 20, 2008)
• ISSN：1523-7052

文摘

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A straightforward and high-yielding access to various [2.2]paracyclophanes possessing a sulfur-based functional group is reported, the keystep being a S_EAr reaction mediated by a sulfonium salt. The versatility of the methodology was exemplified by an original application insulfenate salt chemistry, from which a remarkable chirality transfer was observed.