In Vitro and in Vivo Studies of Single-Walled Carbon Nanohorns with Encapsulated Metallofullerenes and Exohedrally Functionalized Quantum Dots
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- 作者：Jianfei Zhang ; Jiechao Ge ; Michael D. Shultz ; Eunna Chung ; Gurpreet Singh ; Chunying Shu ; Panos P. Fatouros ; Scott C. Henderson ; Frank D. Corwin ; David B. Geohegan ; Alex A. Puretzky ; Christopher M. Rou
- 刊名：Nano Letters
- 出版年：2010
- 出版时间：August 11, 2010
- 年：2010
- 卷：10
- 期：8
- 页码：2843-2848
- 全文大小：415K
- 年卷期：v.10,no.8(August 11, 2010)
- ISSN：1530-6992
文摘
Single-walled carbon nanohorns (SWNHs) are new carbonaceous materials. In this paper, we report the first successful preparation of SWNHs encapsulating trimetallic nitride template endohedral metallofullerenes (TNT-EMFs). The resultant materials were functionalized by a high-speed vibration milling method and conjugated with CdSe/ZnS quantum dots (QDs). The successful encapsulation of TNT-EMFs and external functionalization with QDs provide a dual diagnostic platform for in vitro and in vivo biomedical applications of these new carbonaceous materials.