Hepatoprotective Prenylaromadendrane-Type Diterpenes from the Gum Resin of Boswellia carterii
详细信息 查看全文
- 作者：Yan-gai Wang ; Jin Ren ; Ai-guo Wang ; Jian-bo Yang ; Teng-fei Ji ; Qin-Ge Ma ; Jin Tian ; Ya-lun Su
- 刊名：Journal of Natural Products
- 出版年：2013
- 出版时间：November 22, 2013
- 年：2013
- 卷：76
- 期：11
- 页码：2074-2079
- 全文大小：246K
- 年卷期：v.76,no.11(November 22, 2013)
- ISSN：1520-6025
文摘
Chemical examination of the exuded gum resin of Boswellia carterii resulted in the isolation of nine new prenylaromadendrane-type diterpenes, boscartols A鈥揑 (1鈥?b>9). The structures of these compounds were established by extensive 1D and 2D NMR spectroscopic analyses, mass spectrometric data, and circular dichroism spectra. Compounds 1鈥?b>3, 5, 6, 8, and 9 (10 渭M) showed moderate hepatoprotective activity against d-galactosamine-induced HL-7702 cell damage.