Electroformation of Peptide Self-Assembled Monolayers on Gold

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• 作者：Olivier R. Bolduc ; Debby Correia-Ledo ; Jean-Francois Masson
• 刊名：Langmuir
• 出版年：2012
• 出版时间：January 10, 2012
• 年：2012
• 卷：28
• 期：1
• 页码：22-26
• 全文大小：230K
• 年卷期：v.28,no.1(January 10, 2012)
• ISSN：1520-5827

文摘

The application of a potential to deposit a monolayer of 3-mercaptopropionic acid-histidinyl-histidinyl-histidinyl-aspartyl-aspartyl (3-MPA-HHHDD-OH) controls the density and molecular structure of the peptide monolayer, which results in different wettabilities of the surface, surface density, orientation of the molecule (extended or bent), and nonspecific adsorption of serum proteins. 3-MPA-HHHDD-OH must be deposited at 200 mV to maintain an extended configuration, which promoted low biofouling properties.