Tetra-Antimony(III)-Bridged 18-Tungsto-2-Arsenates(V), [(LSbIII)4(A-α-AsVW9O34)2]10– (L = Ph, OH): Turning Bioactivity On and Off by Ligand Substitution

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• 作者：Peng Yang ; Zhengguo Lin ; Bassem S. Bassil ; Gabriela Alfaro-Espinoza ; Matthias S. Ullrich ; Ming-Xing Li ; Cristian Silvestru ; Ulrich Kortz
• 刊名：Inorganic Chemistry
• 出版年：2016
• 出版时间：April 18, 2016
• 年：2016
• 卷：55
• 期：8
• 页码：3718-3720
• 全文大小：239K
• 年卷期：0
• ISSN：1520-510X

文摘

Two tetra-antimony(III)-bridged, sandwich-type 18-tungsto-2-arsenates(V), [(LSb<sup>IIIsup>)<sub>4sub>(A-α-As<sup>Vsup>W<sub>9sub>O<sub>34sub>)<sub>2sub>]<sup>10–sup> (L = Ph (1), OH (2)), were prepared and fully characterized in the solid state and in solution. Both polyanions are stable in aqueous physiological medium for at least 24 h (at concentrations ≥2.5 × 10<sup>–6sup> M). Despite the presence of an isostructural tetra-antimony(III) motif in 1 and 2, distinctly different antibacterial activity was observed for both polyanions. The minimum inhibitory concentrations (MIC) of 1 (7.8–62.5 μg/mL) is lower than for any other organoantimony(III)-containing polyoxometalate reported to date.