Factors Affecting the Absorption, Metabolism, and Excretion of Cocoa Flavanols in Humans
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- 作者：Tania Cifuentes-Gomez ; Ana Rodriguez-Mateos ; Isidro Gonzalez-Salvador ; Mar铆a Elena Ala帽on ; Jeremy P. E. Spencer
- 刊名：Journal of Agricultural and Food Chemistry
- 出版年：2015
- 出版时间：September 9, 2015
- 年：2015
- 卷：63
- 期：35
- 页码：7615-7623
- 全文大小：366K
- ISSN：1520-5118
文摘
Cocoa is rich in a subclass of flavonoids known as flavanols, the cardiovascular health benefits of which have been extensively reported. The appearance of flavanol metabolites in the systemic circulation after flavanol-rich food consumption is likely to mediate the physiological effects on the vascular system, and these levels are influenced by numerous factors, including food matrix, processing, intake, age, gender, or genetic polymorphisms, among others. This review will focus on our current understanding of factors affecting the absorption, metabolism, and excretion of cocoa flavanols in humans. Second, it will identify gaps in these contributing factors that need to be addressed to conclusively translate our collective knowledge into the context of public health, dietary guidelines, and evidence-based dietary recommendations.