Highly Sensitive Glucose Sensor Based on Pt Nanoparticle/Polyaniline Hydrogel Heterostructures
详细信息 查看全文
- 作者：Dongyuan Zhai ; Borui Liu ; Yi Shi ; Lijia Pan ; Yaqun Wang ; Wenbo Li ; Rong Zhang ; Guihua Yu
- 刊名：ACS Nano
- 出版年：2013
- 出版时间：April 23, 2013
- 年：2013
- 卷：7
- 期：4
- 页码：3540-3546
- 全文大小：414K
- 年卷期：v.7,no.4(April 23, 2013)
- ISSN：1936-086X
文摘
Glucose enzyme biosensors have been shown useful for a range of applications from medical diagnosis, bioprocess monitoring, to beverage industry and environmental monitoring. We present here a highly sensitive glucose enzyme sensor based on Pt nanoparticles (PtNPs)-polyaniline (PAni) hydrogel heterostructures. High-density PtNPs were homogeneously loaded onto the three-dimensional (3D) nanostructured matrix of the PAni hydrogel. The PtNP/PAni hydrogel heterostructure-based glucose sensor synergizes the advantages of both the conducting hydrogel and the nanoparticle catalyst. The porous structure of the PAni hydrogel favored the high density immobilization of the enzyme and the penetration of water-soluble molecules, which helped efficiently catalyze the oxidation of glucose. In addition, the PtNPs catalyzed the decomposition of hydrogen peroxide that was generated during the enzymatic reaction. The transferred charges from these electrochemical processes were efficiently collected by the highly conducting PtNP/PAni hydrogel heterostructures. The glucose enzyme sensor based on this heterostructure exhibited unprecedented sensitivity, as high as 96.1 渭A路mM鈥?路cm鈥?, with a response time as fast as 3 s, a linear range of 0.01 to 8 mM, and a low detection limit of 0.7 渭M.