Mechanism of Rh2(II)-Catalyzed Indole Formation: The Catalyst Does Not Control Product Selectivity

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• 作者：Jason G. Harrison ; Osvaldo Gutierrez ; Navendu Jana ; Tom G. Driver ; Dean J. Tantillo
• 刊名：Journal of the American Chemical Society
• 出版年：2016
• 出版时间：January 20, 2016
• 年：2016
• 卷：138
• 期：2
• 页码：487-490
• 全文大小：353K
• ISSN：1520-5126

文摘

Possible mechanisms for Rh-promoted indole formation from vinyl/azidoarenes were examined computationally, and a mechanism is proposed in which the Rh catalyst promotes generation of a nitrene but is not directly involved in cyclization.