Phase Transfer Activation of Fluorous Analogs of Grubbs鈥?Second-Generation Catalyst: Ring-Opening Metathesis Polymerization

详细信息    查看全文

• 作者：Robert Tuba ; Rosenildo Corr锚a da Costa ; Hassan S. Bazzi ; John A. Gladysz
• 刊名：ACS Catalysis
• 出版年：2012
• 出版时间：January 1, 2012
• 年：2012
• 卷：2
• 期：1
• 页码：155-162
• 全文大小：344K
• 年卷期：v.2,no.1(January 1, 2012)
• ISSN：2155-5435

文摘

Grubbs鈥?second-generation alkene metathesis catalyst and the fluorous analog (H₂IMes)((R_f8(CH₂)₂)₃P)(Cl)₂Ru(鈺怌HPh) (1; H₂IMes/R_f8 = 1,3-dimesityl-4,5-dihydroimidazol-2-ylidene/(CF₂)₇CF₃) catalyze ring-opening metathesis polymerizations of norbornene at essentially identical rates (CDCl₃, RT). However, dramatic accelerations can be observed with 1 in the presence of the fluorous solvent perfluoro(methylcyclohexane) (PFMC). The fluorous phosphine (R_f8(CH₂)₂)₃P must first dissociate from 1 to generate the 14-valence-electron intermediate that begins the catalytic cycle and should be scavenged by the PFMC phase (PFMC/toluene partition coefficient >99.7:<0.3). This would allow alkenes to more effectively compete for active catalyst. However, faster rates are seen only when 1 (partition coefficient 39.6:60.4) is added as a PFMC solution or a PFMC/CDCl₃ biphase mixture, as opposed to CDCl₃ solution, and possible additional contributing factors are analyzed. Analogous effects are observed with a 7-oxanorbornene-based N-butylsuccinimide. The molecular weights, polydispersities, glass transition temperatures, and cis/trans C鈺怌 linkage ratios of the polynorbornene produced under monophasic and biphasic conditions are compared and are usually similar.

Keywords:

ROMP; fluorous; biphase catalysis; phase transfer; Grubbs鈥?catalyst; polynorbornene