(+)- and (?)-Cajanusine, a Pair of New Enantiomeric Stilbene Dimers with a New Skeleton from the Leaves of Cajanus cajan
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- 作者：Xiao-Long Li ; Bing-Xin Zhao ; Xiao-Jun Huang ; Dong-Mei Zhang ; Ren-Wang Jiang ; Ying-Jie Li ; Yu-Qing Jian ; Ying Wang ; Yao-Lan Li ; Wen-Cai Ye
- 刊名：Organic Letters
- 出版年：2014
- 出版时间：January 3, 2014
- 年：2014
- 卷：16
- 期：1
- 页码：224-227
- 全文大小：264K
- ISSN：1523-7052
文摘
A pair of new enantiomeric stilbene dimers, (+)- and (鈭?-cajanusine [(+)-1 and (鈭?-1], with a unique coupling pattern were isolated from the leaves of Cajanus cajan. Their structures including absolute configurations were elucidated on the basis of comprehensive spectroscopic and single-crystal X-ray diffraction analyses, as well as CD calculations. The plausible biogenetic pathway of 1 was also proposed. Additionally, (卤)-1, (+)-1, and (鈭?-1 exhibited inhibitory activities on the growth of human hepatocellular carcinoma cells.