Enantioselective Preparation of a Stable Boronate Complex Stereogenic Only at Boron

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• 作者：Peter F. Kaiser ; Jonathan M. White ; Craig A. Hutton
• 刊名：Journal of the American Chemical Society
• 出版年：2008
• 出版时间：December 10, 2008
• 年：2008
• 卷：130
• 期：49
• 页码：16450-16451
• 全文大小：141K
• 年卷期：v.130,no.49(December 10, 2008)
• ISSN：1520-5126

文摘

Asymmetric synthesis of a boronate complex stereogenic exclusively at boron has been achieved through chirality transfer from a carbon stereocenter that is subsequently abolished. The boronate complex is formed with >99% ee and is remarkably configurationally stable, with no racemization observed after 24 h at 110°.