Stereoselective Intermolecular Nitroaminoxylation of Terminal Aromatic Alkynes: Trapping Alkenyl Radicals by TEMPO
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- 作者：Hong Yan ; Guangwei Rong ; Defu Liu ; Yang Zheng ; Jie Chen ; Jincheng Mao
- 刊名：Organic Letters
- 出版年：2014
- 出版时间：December 19, 2014
- 年：2014
- 卷：16
- 期：24
- 页码：6306-6309
- 全文大小：371K
- ISSN：1523-7052
文摘
The vinyl radical is one of the most unstable organic radicals. It is demonstrated that a nitro radical attacks phenylacetylene and makes the phenyl ring deconjugated with a double bond so that the resulting vinyl radical may be stabilized by delocalization to the phenyl ring鈥檚 蟺 orbital and easily trapped by TEMPO. It is noteworthy that all desired products were obtained in moderate to good yields in an (E)-configuration.