Mechanistic Study of the Oxidative Coupling of Styrene with 2-Phenylpyridine Derivatives Catalyzed by Cationic Rhodium(III) via C鈥揌 Activation
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- 作者：Mika毛l Brasse ; Juan C谩mpora ; Jonathan A. Ellman ; Robert G. Bergman
- 刊名：The Journal of the American Chemical Society
- 出版年：2013
- 出版时间：May 1, 2013
- 年：2013
- 卷：135
- 期：17
- 页码：6427-6430
- 全文大小：306K
- 年卷期：v.135,no.17(May 1, 2013)
- ISSN：1520-5126
文摘
The Rh(III)-catalyzed oxidative coupling of alkenes with arenes provides a greener alternative to the classical Heck reaction for the synthesis of arene-functionalized alkenes. The present mechanistic study gives insights for the rational development of this key transformation. The catalyst resting states and the rate law of the reaction have been identified. The reaction rate is solely dependent on the catalyst and alkene concentrations, and the turnover-limiting step is the migratory insertion of the alkene into a Rh鈥揅(aryl) bond.