Platinum-Catalyzed Intramolecular Hydroarylation of Allenyl Arenes: Efficient Synthesis of 1,4-Dihydronaphthalenes

详细信息    查看全文

• 作者：Juntae Mo ; Phil Ho Lee
• 刊名：Organic Letters
• 出版年：2010
• 出版时间：June 4, 2010
• 年：2010
• 卷：12
• 期：11
• 页码：2570-2573
• 全文大小：198K
• 年卷期：v.12,no.11(June 4, 2010)
• ISSN：1523-7052

文摘

An efficient synthetic method of 1,4-dihydronaphthalenes having various alkyl groups on the 4-position and/or ethoxycarbonyl group on the 2-position through selective intramolecular Pt-catalyzed 6-endo cyclohydroarylation of ethyl 2-benzyl-2,3-alkadienoates was developed. The present method could be further extended to two-fold Pt-catalyzed 6-endo and 7-endo cyclizations.