Direct Aqueous Injection LC−ESI/MS/MS Analysis of Water for 11 Chloro- and Thiomethyltriazines and Metolachlor and Its Ethanesulfonic and Oxanilic Acid Degradates

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• 作者：Sung-Ben Huang ; Thomas J. Mayer ; Robert A. Yokley
• 刊名：Journal of Agricultural and Food Chemistry
• 出版年：2008
• 出版时间：April 23, 2008
• 年：2008
• 卷：56
• 期：8
• 页码：2595 - 2602
• 全文大小：637K
• 年卷期：v.56,no.8(April 23, 2008)
• ISSN：1520-5118

文摘

A multianalyte method is reported for the determination of atrazine, simazine, propazine, and their respective dealkylated chlorotriazine metabolites; ametryn and prometryn and their respective dealkylated thiomethyltriazine metabolites; and S-metolachlor and its ethanesulfonic and oxanilic acid degradates in deionized, ground, surface, and finished drinking water. Water samples are analyzed using direct aqueous injection (DAI) liquid chromatography−electrospray ionization/mass spectrometry/mass spectrometry (LC−ESI/MS/MS). No preanalysis sample manipulation is required other than transfer of a small portion of sample to an injection vial. The lower limit of the method validation is 0.050 µg/L (ppb) for all analytes except 2,4-diamino-6-chloro-s-triazine (didealkylatrazine, DDA, or G-28273). For this compound the LLMV is 0.50 µg/L (ppb). The overall mean procedural recoveries (and percent relative standard deviations) for all water types for all analytes ranged from 95 to 101% (4.5−11%). The method validation was conducted under U.S. EPA FIFRA Good Laboratory Practice Guidelines 40 CFR 160.