Amine-Promoted, Organocatalytic Aziridination of Enones

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• 作者：Alan Armstrong ; Carl A. Baxter ; Scott G. Lamont ; Andrew R. Pape ; Richard Wincewicz
• 刊名：Organic Letters
• 出版年：2007
• 出版时间：January 18, 2007
• 年：2007
• 卷：9
• 期：2
• 页码：351 - 353
• 全文大小：67K
• 年卷期：v.9,no.2(January 18, 2007)
• ISSN：1523-7052

文摘

A novel method is presented using N-N ylides (prepared by in situ amination of a tertiary amine) for the aziridination of a range of enonesystems. The amine may be used sub-stoichiometrically, and promising levels of enantioselectivity are observed with quinine as promoter.