Thiol-Functionalized Gold Nanodots: Two-Photon Absorption Property and Imaging In Vitro
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- 作者：Chien-Liang Liu ; Mei-Lin Ho ; Yu-Chun Chen ; Cheng-Chih Hsieh ; Yi-Chih Lin ; Yu-Hsiu Wang ; Meng-Ju Yang ; Hsin-Sheng Duan ; Bo-So Chen ; Jyh-Fu Lee ; Jong-Kai Hsiao ; Pi-Tai Chou
- 刊名：Journal of Physical Chemistry C
- 出版年：2009
- 出版时间：December 17, 2009
- 年：2009
- 卷：113
- 期：50
- 页码：21082-21089
- 全文大小：281K
- 年卷期：v.113,no.50(December 17, 2009)
- ISSN：1932-7455
文摘
We report here the study of two-photon induced luminescence of 11-mercaptoundecanoic acid functionalized quantum-sized Au nanodots (11MUA-Au nanodots). The X-ray absorption near-edge structure (XANES) measurement at the gold LIII edge indicates that the oxidation state of the surface of 11MUA-Au nanodots is best described as Au+. The two-photon absorption (TPA) property of 11MUA-Au nanodots was then investigated via an open aperture Z-scan method. Together with a precise extinction coefficient (i.e., one-photon absorption) extracted from inductively coupled plasma mass spectrometry, the TPA cross section, σ, was deduced to be 8761 ± 175 GM (800 nm) for 11MUA-Au nanodots (diameter 1.33 ± 0.12) in water. Upon dextran encapsulation, 11MUA-Au nanodots was proved to be highly water-soluble, stable, and low in toxicity, which demonstrated its power in two-photon imaging toward human mesenchymal stem cells (hMSCs) in vitro.