Pestaloquinols A and B, Isoprenylated Epoxyquinols from Pestalotiopsis sp.

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• 作者：Gang Ding ; Fan Zhang ; Hong Chen ; Liangdong Guo ; Zhongmei Zou ; Yongsheng Che
• 刊名：Journal of Natural Products
• 出版年：2011
• 出版时间：February 25, 2011
• 年：2011
• 卷：74
• 期：2
• 页码：286-291
• 全文大小：830K
• 年卷期：v.74,no.2(February 25, 2011)
• ISSN：1520-6025

文摘

Two new isoprenylated epoxyquinol derivatives, pestaloquinols A (2) and B (3), and their putative biosynthetic precursor, cytosporin D (1), were isolated from the crude extract of the plant endophytic fungus Pestalotiopsis sp. The structures of these compounds were elucidated primarily by NMR experiments. Pestaloquinols A (2) and B (3) possess a previously undescribed nonacyclic ring system and showed cytotoxicity against HeLa cells.