Transition-Metal-Free Fluoroarylation of Diazoacetamides: A Complementary Approach to 3-Fluorooxindoles

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• 作者：Kuiyong Dong ; Bin Yan ; Sailan Chang ; Yongjian Chi ; Lihua Qiu ; Xinfang Xu
• 刊名：Journal of Organic Chemistry
• 出版年：2016
• 出版时间：August 5, 2016
• 年：2016
• 卷：81
• 期：15
• 页码：6887-6892
• 全文大小：405K
• 年卷期：0
• ISSN：1520-6904

文摘

An efficient transition-metal-free fluoroarylation reaction of N-aryl diazoacetamides with NFSI (N-fluorobenzenesulfonimide) is described. This reaction directly provides 3-fluorooxindole derivatives in yields of 67–93% with high selectivity via a carbene-free process under mild reaction conditions.