Simultaneous Determination of Perfluorinated Compounds in Edible Oil by Gel-Permeation Chromatography Combined with Dispersive Solid-Phase Extraction and Liquid Chromatography鈥揟andem Mass Spectrometry

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• 作者：Lili Yang ; Fen Jin ; Peng Zhang ; Yanxin Zhang ; Jian Wang ; Hua Shao ; Maojun Jin ; Shanshan Wang ; Lufei Zheng ; Jing Wang
• 刊名：Journal of Agricultural and Food Chemistry
• 出版年：2015
• 出版时间：September 30, 2015
• 年：2015
• 卷：63
• 期：38
• 页码：8364-8371
• 全文大小：510K
• ISSN：1520-5118

文摘

A simple analytical method was developed for the simultaneous analysis of 18 perfluorinated compounds (PFCs) in edible oil. The target compounds were extracted by acetonitrile, purified by gel permeation chromatography (GPC) and dispersive solid-phase extraction (DSPE) using graphitized carbon black (GCB) and octadecyl (C₁₈), and analyzed by liquid chromatography鈥揺lectrospray ionization tandem mass spectrometry (LC-ES-MS/MS) in negative ion mode. Recovery studies were performed at three fortification levels. The average recoveries of all target PFCs ranged from 60 to 129%, with an acceptable relative standard deviation (RSD) (1鈥?0%, n = 3). The method detection limits (MDLs) ranged from 0.004 to 0.4 渭g/kg, which was significantly improved compared with the existing liquid鈥搇iquid extraction and cleanup method. The method was successfully applied for the analysis of all target PFCs in edible oil samples collected from markets in Beijing, China, and the results revealed that C₆鈥揅₁₀ perfluorocarboxylic acid (PFCAs) and C₇ perfluorosulfonic acid PFSAs were the major PFCs detected in oil samples.