Styryl Conjugated Coumarin Caged Alcohol: Efficient Photorelease by Either One-Photon Long Wavelength or Two-Photon NIR Excitation

详细信息    查看全文

• 作者：Chunyan Bao ; Guanshui Fan ; Qiuning Lin ; Bo Li ; Shuiyu Cheng ; Qi Huang ; Linyong Zhu
• 刊名：Organic Letters
• 出版年：2012
• 出版时间：January 20, 2012
• 年：2012
• 卷：14
• 期：2
• 页码：572-575
• 全文大小：259K
• 年卷期：v.14,no.2(January 20, 2012)
• ISSN：1523-7052

文摘

The synthesis and photorelease properties of a new phototrigger for alcohols are described. Compared to ester 4 caged by the reported [7-(diethylamino)coumarin-4-yl]methoxycarbonyl (DEACM) phototrigger, the caged ester 3 shows an efficient single-photon photolysis efficiency upon irradiation of long wavelength light (位 = 475 nm) and a stronger two-photon photolysis sensitivity with 800 nm laser light. Its promising properties and the efficient photorelease of adenosine make it very useful as a caging group for biological applications.