Pd(0)-Catalyzed 1,1-Diarylation of Ethylene and Allylic Carbonates

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• 作者：Vaneet Saini ; Longyan Liao ; Qiaofeng Wang ; Ranjan Jana ; Matthew S. Sigman
• 刊名：Organic Letters
• 出版年：2013
• 出版时间：October 4, 2013
• 年：2013
• 卷：15
• 期：19
• 页码：5008-5011
• 全文大小：307K
• 年卷期：v.15,no.19(October 4, 2013)
• ISSN：1523-7052

文摘

An efficient protocol for the one-step synthesis of biologically relevant 1,1-diarylalkanes has been described. This reaction introduces two different aryl groups across the terminal end of simple feedstock alkenes such as ethylene and allylic carbonates. The propensity to generate 蟺-benzylpalladium intermediates dictates the exclusive 1,1-regioselectivity observed in the product.