Triazolylpyrenes: Synthesis, Fluorescence Properties, and Incorporation into DNA
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- 作者：Sarah Werder ; Vladimir L. Malinovskii ; Robert Hä ; ner
- 刊名：Organic Letters
- 出版年：2008
- 出版时间：May 15, 2008
- 年：2008
- 卷：10
- 期：10
- 页码：2011 - 2014
- 全文大小：583K
- 年卷期：v.10,no.10(May 15, 2008)
- ISSN：1523-7052
文摘
Synthesis of 1,6- and 1,8-triazolylpyrenes and their incorporation into oligonucleotides is described. In hybrids, triazolylpyrenes adopt interstrand stacking interactions. Exciton coupling is observed for the duplex containing a pair of the 1,6-isomer indicating a well-defined helical arrangement of the triazolylpyrene building blocks. Triazole substitution results in pronounced red-shifts of monomer as well as excimer fluorescence. Furthermore, quantum yields of the formed excimers are remarkably high.