文摘
Linear diterpenes isolated from aerial parts of Baccharis thymifolia (1–3) were tested for insect growth inhibitory activity against Tenebrio molitor larvae. Compounds 4–16 were prepared by various chemical transformations. The diterpenes 6,10-(E,E)-thymifodioic acid (1), the butenolide 3, and the derivatives 4, 11, and 14 produced developmental deficiencies in assays using topical application on fifth instar larvae of T. molitor. Compound 3 is a new natural product.