Penicillipyrones A and B, Meroterpenoids from a Marine-Derived Penicillium sp. Fungus

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• 作者：Lijuan Liao ; Jung-Ho Lee ; Minjung You ; Tae Joon Choi ; Wanki Park ; Sang Kook Lee ; Dong-Chan Oh ; Ki-Bong Oh ; Jongheon Shin
• 刊名：Journal of Natural Products
• 出版年：2014
• 出版时间：February 28, 2014
• 年：2014
• 卷：77
• 期：2
• 页码：406-410
• 全文大小：248K
• 年卷期：v.77,no.2(February 28, 2014)
• ISSN：1520-6025

文摘

Penicillipyrones A (1) and B (2), two novel meroterpenoids, were isolated from the marine-derived fungus Penicillium sp. On the basis of the results of combined spectroscopic analyses, these compounds were structurally elucidated to be sesquiterpene 纬-pyrones from a new skeletal class derived from a unique linkage pattern between the drimane sesquiterpene and pyrone moieties. Compound 2 elicited significant induction of quinone reductase.