Switching the Adhesive State of Catecholic Hydrogels using Phototitration

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• 作者：Evan M. White ; Jonathan E. Seppala ; Parker M. Rushworth ; Branson W. Ritchie ; Suraj Sharma ; Jason Locklin
• 刊名：Macromolecules
• 出版年：2013
• 出版时间：November 26, 2013
• 年：2013
• 卷：46
• 期：22
• 页码：8882-8887
• 全文大小：333K
• 年卷期：v.46,no.22(November 26, 2013)
• ISSN：1520-5835

文摘

A polyacrylamide hydrogel system that can be liquefied by remote activation using UV irradiation is investigated as a degradable adhesive. The linear polyacrylamide copolymer, formed by conventional free-radical polymerization, contains biomimetic catechol鈥搃ron-mediated cross-linkers that are sensitive to pH changes. Hydrogel films and bulk gels are prepared by basic titration of a polymer solution doped with a photoacid generator, diphenyliodonium chloride, generating an ionic cross-linked network via the catechol pendant groups. Irradiation of these hydrogels with UV light affords a viscous liquid solution, demonstrating a gel鈥搒ol transition with a subsequent decrease in the adhesive strength of the material. These gels may be prepared in high throughput and require few synthetic steps with commercially available precursors.